Publications

I've given links, pdfs of the main text and supplementary material, and talk slides when available.
A pubmed list of publications is here.

* - denotes an equal contribution

2010

Parallel adaptation: One or many waves of advance of an advantageous allele? Ralph PL, Coop G. Submitted.

Using Environmental Correlations to Identify Loci Underlying Local Adaptation. Coop G., Witonsky D., Di Rienzo A., Pritchard J.K. Genetics. 2010

Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency 1. Hancock AM, Witonsky D, Ehler E, Alkorta-Aranburu G, Beall C, Amha Gebremedhin,Sukernik R, Utermann G, Pritchard JK, Coop G, Di Rienzo PNAS 2010

The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation. Prichard JK, Pickrell JK, Coop G. Current Biology. 2010

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice . Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, Coop G, de Massy B (2010) Science. See also the papers by Myers et al. and Parvanov et al. that appeared in the same issue.

2009

Broad-Scale Recombination Patterns Underlying Proper Disjunction in Humans Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G*, Przeworski M.* (2009) PLoS Genetics

Expression quantitative trait loci detected in cell lines are often present in primary tissues. Bullaughey K, Chavarria CI, Coop G*, Gilad Y.* (2009) Hum Mol Genet. pdf

The role of geography in human adaptation Coop G*, Pickrell JK*, Novembre J, Kudaravalli S, Li J, Absher D, Myers RM, Cavalli-Sforza LL, Feldman MW, Pritchard JK. (2009) PLoS Genetics

Signals of recent positive selection in a worldwide sample of human populations. Pickrell JK, Coop G, Novembre J, Kudaravalli S, Li J, Absher D, Srinivasan B, Barsh GS, Myers RM, Feldman MW, Pritchard JK. (2009) Genome Research

An approximate likelihood for genetic data under a model with recombination and population splitting Davison D, Pritchard JK, Coop G. (2009) Theor. Pop. Bio.

2008

The timing of selection at the human FOXP2 gene. Coop, G., Bullaughey, K., Luca, F., and M. Przeworski, 2008 Mol Biol Evol.25(7):1257-9 pdf , Supplementary info.

Using population mixtures to optimize the utility of genomic databases: linkage disequilibrium and association study design in India. Pemberton TJ, Jakobsson M, Conrad DF, Coop G, Wall JD, Pritchard JK, Patel PI, Rosenberg NA. 2008 Ann Hum Genet. 72:535-46

No effect of recombination on the efficacy of natural selection in primates. Bullaughey K, Przeworski M*, Coop G* 2008 Genome Research. pdf , Supplementary info.

High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Coop G, Wen X, Ober C, Pritchard JK, Przeworski M. Science, 2008, pdf , Slides, Data

Adaptations to Climate in Candidate Genes for Common Metabolic Disorders. Hancock MA, Witonsky DB, Gordon AS, Eshel G, Pritchard JK, Coop G, Di Rienzo A PLoS Genetics 2008.

2007

Adaptive drool in the gene pool Novembre J*, Pritchard JK, Coop G*, Nature Genetics, 2007

Live Hot, Die Young: Transmission Distortion in Recombination Hotspots Coop G*, Myers S*, PLoS Genetics, 2007 pdf , Slides

An evolutionary view of human recombination. Coop G, Przeworski M. Nat Rev Gen, 2007 pdf

2006

Sequencing and analysis of Neanderthal genomic DNA. Noonan JP, Coop G, Kudaravalli S, Smith D, Krause J, Alessi J, Chen F, Platt D, Paabo S, Pritchard JK, Rubin EM. Science. 2006, 314:1113-8. pdf , Slides

How reliable are empirical genomic scans for selective sweeps? Teshima KM, Coop G, Przeworski M., Genome Res. 2006 (selected by Faculty of 1000) pdf

A worldwide survey of haplotype variation and linkage disequilibrium in the human genome Conrad DF*, Jakobsson M*, Coop G*, Wen X, Wall JD, Rosenberg NA, Pritchard JK., Nat Gen 2006 pdf

Combining sperm typing and LD analyses reveals differences in selective pressures or recombination rates across human populations. Clark V, Ptak SE, Tiemann-Boege I, Qian Y, Coop G, Stone AC, Przeworski M, Arnheim N, Di Rienzo A. Genetics. 2006 pdf

Screening for recently selected alleles by analysis of human haplotype similarity. Hanchard NA, Rockett KA, Spencer C, Coop G, Pinder M, Jallow M, Kimber M, McVean G, Mott R, Kwiatkowski DP. American Journal of Human Genetics, 2006 Jan;78(1):153-9

Spread of an Inactive Form of Caspase-12 in Humans Is Due to Recent Positive Selection Yali Xue, Allan Daly, Bryndis Yngvadottir, Mengning Liu, Graham Coop, Yuseob Kim, Pardis Sabeti, Yuan Chen, Jim Stalker, Elizabeth Huckle, John Burton, Steven Leonard, Jane Rogers, and Chris Tyler-Smith. American Journal of Human Genetics, 2006, Apr;78(4):659-70

2005

The signature of positive selection on standing genetic variation. Przeworski M, Coop G, Wall JD. Evolution 2005. pdf

Can a genome change its (hot)spots. Coop G. Trends in Ecology and Evolution. Dec 2005; 20 (12), 643-645 pdf

The rise and fall of the chemoattractant receptor GPR33. Rompler H, Schulz A, Pitra C, Coop G, Przeworski M, Paabo S, Schoneberg T. J Biol Chem. 2005, PubMed

2004

SelSim: a program to simulate population genetic data with natural selection and recombination. Spencer C.C.A., Coop G. Bioinformatics. Jul 2004, 22 pdf

Darwinian Selection on a Selfing Locus. Shimizu KK, Cork JM, Caicedo AL, Mays CA, Moore RC, Olsen KM, Ruzsa S, Coop G, Bustamante CD, Awadalla P, Purugganan MD. Science. 2004, 306 (5704), 2081-4. pdf This article was later retracted due to PCR errors;

Ancestral inference on gene trees under selection. Coop G. , Griffiths R. C., Theor Popul Biol, Nov 2004; 66 (3); 219-32. pdf ; (selected by Faculty of 1000)

The Likelihood of Gene Trees under Selective Models. Coop G., DPhil. Thesis, 2004. pdf